Testosterone injections are intramuscular, which means that they are given into the muscles. There are 2 common places to inject Testosterone. The most muscular part of your body known as your “glutes”/ “buttocks” is the preferred place for Testosterone Injections. Specifically, the safest area to inject is the upper outer glute to ensure you miss the sciatic nerve. The far less common area is the thigh, due to the high probability of hitting the femur (bone below the quadriceps).