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Growth Hormone Deficiency: What Adults Over 30 Need to Know


If you are over thirty, you need to understand some basic information about adult-onset growth hormone deficiency. The information provided here is essential due to increased risks of premature mortality often associated with hypopituitarism.

What is HGH deficiency? Adults begin to experience a decline in human growth hormone production by the time they enter their thirties. Symptoms may not manifest for years or even decades. Many people naturally adjust to lower levels of HGH in the bloodstream. Some do not.

Individuals who experience growth hormone deficiency symptoms are at increased risk of other health concerns, such as:

  • Cardiovascular disease
  • Stroke
  • Diabetes
  • Obesity
  • Osteoporosis
  • Atherosclerosis
  • Dementia
  • High blood pressure

Correcting the decline of growth hormone secretion with HGH therapy can reduce those risks.

Symptoms of a growth hormone deficiency in adults may include any of the following:

  • Fatigue, lethargy, reduced endurance
  • Slow metabolism, weight gain
  • Muscle mass decline, loss of strength
  • Decreased bone density, height shrinkage, joint pains, physical stiffness
  • Sensitivity to temperature changes
  • Increased wrinkles, sagging skin, cellulite, age spots, thinning skin
  • Brittle nails
  • Reduced night vision, decreased eyesight
  • Thinning, balding hair, color turning to grey
  • Memory loss, poor cognitive functions, lack of focus
  • Frequent illness, long recovery times, slow healing
  • Depression, mood changes, social isolation
  • Insomnia, difficulty falling and staying asleep
  • Internal organ shrinkage due to impaired cell regeneration
  • High cholesterol levels
  • Low libido, erectile dysfunction, vaginal dryness
  • Symptoms of PMS or menopause

What Causes Adult Growth Hormone Deficiency?

Adult growth hormone deficiency causes vary. Some people still have low HGH levels leftover from childhood. If GH shortage was not diagnosed as a child, it will likely continue into adulthood. Individuals who received HGH therapy during adolescence may require it again as they age.

Other causes of growth hormone deficiency in adults include:

  • Pituitary tumor
  • Radiation or surgical removal of a brain tumor
  • Traumatic brain injury
  • Excessive alcohol exposure
  • Tumor or injury to the hypothalamus
  • Certain genetic abnormalities
  • Aging or idiopathic (no known cause)

How Do Doctors Diagnose Adult Growth Hormone Deficiency?

Doctors specializing in hormonal imbalances determine a growth hormone deficiency diagnosis following these steps:

  • Consultation with the individual to discuss symptoms, medical issues, and lifestyle habits
  • Blood analysis of various markers and hormone levels
  • Physical examination to rule out other health concerns
  • Review of the completed medical history form

The growth hormone deficiency test measures insulin growth factor 1 levels in the blood. IGF-1 is a hormone secreted by the liver in response to the amount of HGH it receives. Due to IGF-1 levels remaining relatively constant during the day, it is a better measurement than HGH which fluctuates significantly.

Only individuals with low HGH levels and associative symptoms require human growth hormone therapy.

What to Do When You Have Growth Hormone Deficiency

Once you are diagnosed with a growth hormone deficiency, the doctor will assess the amount of HGH you require. Age, body composition, general health, and symptom severity are used to determine HGH dosage.

Your medical advisor here at Kingsberg Medical will discuss treatment options with you. Growth hormone deficiency that causes widespread symptoms requires treatment with HGH injections. HGH immediately increases the amount of growth hormone available to the body.

Individuals in the preliminary stages of GH decline can sometimes use sermorelin injections in place of HGH. Sermorelin stimulates the pituitary gland to increase growth hormone output. It works at a slower pace but is less expensive and an excellent choice to improve pituitary functions. Sermorelin is not an option for individuals suffering from extreme growth hormone deficiency.

To prevent the symptoms of HGH deficiency, adults should focus on these lifestyle habits:

  • Getting enough sleep – 7 to 9 hours every night is crucial to optimize HGH secretion at night
  • Getting enough exercise – the pituitary gland increases HGH output in response to high-intensity interval training – 3 to 4 times a week, for 20 to 30 minutes
  • Intermittent fasting – HGH secretion increases significantly when you find a form of intermittent fasting that works for you – eating all food between noon and 6 pm is an excellent option
  • Reducing stress – when you are stressed, your body secretes cortisol which inhibits HGH production

Contact Kingsberg Medical to find out more about growth hormone deficiency and how to optimize HGH levels. Consultations are confidential and provided at no charge.