In the HGH injection kits that still use insulin syringes, the needles are very thin, much like the ones that diabetics use to administer insulin shots, and are barely noticeable beyond a pinch when done correctly. Some of the newer HGH injection pen systems use premeasured auto-injector and have needle tips, that are similar to insulin syringes, but only require the needle tip be threaded on before each injection. These injections are also very easy, quick, and can be delivered with little or no pain at all.